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In fact, it’s thought that up to 88% of people following these diets have a deficiency ( This is because B12 is only found naturally in animal foods
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(149458) 79 or/65-78 (2267662) 80 64 and 79 (157) 81 80 use emez (124) 82 41 or 81 (158) 83 82 use medall (32) 84 82 use emez (124) 85 82 use cctr (1) 86 82 use coch (0) 87 82 use clhta (1) 88 82 use cleed (0) 89 remove duplicates from 82 (125) Grey Literature Search Performed : February 20–25, 2020 Websites searched : HTA Database Canadian Repository, Alberta Health Evidence Reviews, BC Health Technology Assessments, Canadian Agency for Drugs and Technologies in Health (CADTH), Institut national d'excellence en santé et en services sociaux (INESSS), Institute of Health Economics (IHE), McGill University Health Centre Health Technology Assessment Unit, Centre Hospitalier de l'Universite de Quebec-Universite Laval, Health Technology Assessment Database, Epistemonikos, National Institute for Health and Care Excellence (NICE), Agency for Healthcare Research and Quality (AHRQ) Evidence-based Practice Centers, Australian Government Medical Services Advisory Committee, Council of Australian Governments Health Technologies, Centers for Medicare & Medicaid Services Technology Assessments, Institute for Clinical and Economic Review, Ireland Health Information and Quality Authority Health Technology Assessments, Washington State Health Care Authority Health Technology Reviews, Health Technology Wales, Oregon Health Authority Health Evidence Review Commission, Veterans Affairs Health Services Research and Development, Italian National Agency for Regional Health Services (AGENAS), Australian Safety and Efficacy Register of New Interventional Procedures −Surgical (ASERNIP-S), Belgian Health Care Knowledge Centre, Ludwig Boltzmann Institute for Health Technology Assessment, Ministry of Health Malaysia Health Technology Assessment Section, Swedish Agency for Health Technology Assessment and Assessment of Social Services, PROSPERO, EUnetHTA, Tuft's Cost-Effectiveness Analysis Registry, SickKids Paediatric Economic Database Evaluation (PEDE) database Keywords used : DPYD, DPD, Dihydropyrimidine Dehydrogenase, Fluorouracil, Fluoropyrimidine, 5FU, toxicity Clinical results (included in PRISMA): 5 Economic results (included in PRISMA): 5 Ongoing HTAs (PROSPERO/EUnetHTA/MSAC): 4 Ongoing RCTs (clinicaltrials.gov): 91 Appendix 2: Characteristics of Included Studies Table A1: Abbreviations: 5-FU, 5-fluorouracil
