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demonstrates potential in ameliorating paraquat-induced lung injury and fibrosis by mitigating oxidative stress and ferroptosis through the Nrf2/HO-1 pathway, which further underscores the crucial regulatory role of this pathway in the PF progression [116]

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Dietary flavonoid genistein induces Nrf2 and phase II detoxification gene expression via ERKs and PKC pathways and protects against oxidative stress in Caco-2 cells