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A study examining choline intake in 664 subjects enrolled in the cross-sectional study Nonalcoholic Steatohepatitis (NASH) Clinical Research Network (NCT00063622 and NCT00063635) showed that postmenopausal women with self-reported choline intake less than 50% of the adequate intake, had faster progression of NASH as shown by increased liver fibrosis, while no associations were found in children, men, and premenopausal women (51)
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[DOI] [PMC free article] [PubMed] [Google Scholar] [208].Vrijheid M, Fossati S, Maitre L, Marquez S, Roumeliotaki T, Agier L, Andrusaityte S, Cadiou S, Casas M, de Castro M, Dedele A, Donaire-Gonzalez D, Grazuleviciene R, Haug LS, McEachan R, Meltzer HM, Papadopouplou E, Robinson O, Sakhi AK, Siroux V, Sunyer J, Schwarze PE, Tamayo-Uria I, Urquiza J, Vafeiadi M, Valentin A, Warembourg C, Wright J, Nieuwenhuijsen MJ, Thomsen C, Basagana X, Slama R, Chatzi L, Early-Life Environmental Exposures and Childhood Obesity: An Exposome-Wide Approach, Environ