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The involvement of the NLRP3 inflammasome pathway has also been implicated, with pharmacological inhibition of TLR4/NF-κB/NLRP3 signaling attenuating neuroinflammation and improving tinnitus behavior in noise-exposed mice (Luo et al., 2024)

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This simplicity is particularly appealing to individuals with busy lifestyles who prefer self-administration without the need for medical supervision