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[5] But the pivotal Phase 2b obesity trial did not beat placebo on its primary weight-loss endpoint, was never published in a peer-reviewed journal, and led to the discontinuation of the obesity program — which is why later obesity-pharmacotherapy reviews list AOD-9604 only as an experimental agent, not an effective one

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Because this fragment doesn’t engage the standard hGH receptor pathway, it also doesn’t register on the WADA hGH isoform immunoassay a detail confirmed in peer-reviewed pharmacology research and one of the clearest proof points that AOD-9604’s mechanism is genuinely distinct from full hGH, not just a smaller dose of the same effect