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Antioxidant Treatment Induces Hyperactivation of the HPA Axis by Upregulating ACTH Receptor in the Adrenal and Downregulating Glucocorticoid Receptors in the Pituitary - PMC

Additionally, the severity of protein carbonylation in this model corresponded to diminished expression of major facilitator superfamily domain-containing protein 2A (Mfsd2a) (Figure 4D), a sensitive marker of BBB transcellular activity impairment [33]

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Conclusion: Proper coding of diabetes complications plays a critical role in clinical documentation, reimbursement accuracy, and chronic disease management