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Additionally, binding to nuclear substances can activate related nucleic acid receptors (TLR7/9, cGAS, etc.) to mediate the mass production of IFNs, and subsequently, IFNs can promote ferroptosis and accelerate the release of HMGB1

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As the dimerization of Met is a critical initial event for intracellular tyrosine transphosphorylation, our data indicate that the bell-shaped responses in phosphorylation of Met (Fig