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The T[SH] 2 molecules deliver reducing equivalents to peroxidases and other enzymes responsible for neutralizing ROS, and the oxidized form of trypanothione is reduced by trypanothione reductase (TryR) in presence of NADPH produced by the pentose phosphate pathway (PPP) (discussed below and reviewed in Irigoín et al., 2008)

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If the current obsession with peptides is any indication, many patients will probably take the chance on these unproven products