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On the other hand, double Ghr ko/ Igf1 ko resulted in further postnatal growth retardation relative to Igf1 ko mice completely obstructing further weight gain after postnatal day 15 and supporting previous studies suggesting that progenitor cells in the growth plate require direct GH actions (24)

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Researchers noted evidence of cartilage repair and potential reduction in surgical need, representing one of the most cited human clinical data points for intra-articular BPC-157 use