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Especially high concentrations of this receptor on the apical dendrites of pyramidal cells in layer V of the cortex may modulate cognitive processes, working memory, and attention [34] [35] [36] by enhancing glutamate release followed by a complex range of interactions with the 5-HT 1A , [37] GABA A , [38] adenosine A 1 , [39] AMPA, [40] mGluR 2/3 , [41] mGlu5, [42] and OX 2 receptors

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Cell 32 , 719–730 (2015)