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SCFA, short chain fatty acids

Congested pores

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These strategies overcome major limitations of curcumin therapy, facilitating clinically relevant tissue concentrations capable of modulating oxidative stress markers (ROS, MDA, GSH), inflammatory cytokines (TNF- α , IL-6, IL-1β), amyloid-beta aggregation, tau phosphorylation, and apoptotic signaling (9, 10)