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Furthermore, curcumin treats AD by preventing Aβ plaque development, reducing tau hyperphosphorylation, binding to copper, lowering cholesterol, altering microglial activity, blocking acetylcholinesterase, and acting as an antioxidant [112]

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Microbial fermentation of dietary substrates yields SCFAs, among which acetate, propionate, and butyrate are particularly prominent and functionally relevant (129)