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Taken together, these data show that the Rb C-terminal helix is sufficient to direct cyclin D-Cdk4,6 complexes for phosphorylation, regardless of intrinsic preferences for particular Cdk sites since it enhances phosphorylation for both the relatively weak and strong Cdk phosphorylation sites that we tested (Figure S4)

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Extracellular haemoglobin, oxidative stress and quality of red blood cells relative to perioperative blood salvage