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(2016) demonstrated decreased aortic calcification by VitK2 involving the Gas6/Axl survival pathway using a rat model of warfarin‐induced calcification

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Using the intranasal method in animal models, researchers have successfully reduced stroke damage, reversed Alzheimer's neurodegeneration, reduced anxiety, improved memory, and delivered neurotrophic factors and neural stem cells to the brain [30, 31, 34–37]