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First, we accentuate the bidirectional vicious cycle between α -syn aggregation and ferroptosis, elaborating not only on how α-syn disrupts iron homeostasis and drives lipid peroxidation, but also how iron and its associated oxidative metabolites directly stabilize α-syn oligomers and accelerate fibrillation

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doi: 10.3390/cells10071647 27 ZhangHWangSQHangLZhangCFWangLDuanCJet al