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Likewise, in control groups, female mice have higher abundance of Lactobacillaceae and Streptococcaceae, with lower abundance of Lachnospiraceae and Clostridiaceae than males

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However, some ROS and H 2 O 2, in particular, function not only as damaging species but also as signaling molecules, triggering pathways, such as the JNK/p38MAPK pathway, which can activate p53 independently of the DNA damage response

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