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Curcumin could reduce the infiltration of inflammatory cells and the levels of pro‐inflammatory factors, COX‐2, ROS, and MDA, inhibit the expression of ERS‐related proteins (CHOP, GRP78) and pro‐fibrotic factor TGF‐β, while increasing the activity of antioxidant enzymes and the expression of autophagy‐related proteins, and up‐regulate the level of HDAC2 in COPD animal models (Gan et al

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