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In these derivatives, the iron-binding activity has been significantly reduced

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In a kainic acid (KA)-induced seizure model in rats, co-activation of GABA receptor agonists (felicitin and baclofen) achieves neuroprotection by attenuating the Fas/FasL apoptotic signaling pathway, inhibiting erythrocyanine-induced increase in thioredoxin reductase activity, inhibiting procaspase-3 activation, and decreasing caspase-3 cleavage [62]

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