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Inhibition of system x c − not only has anxiolytic, but also antidepressant potential, as evidenced by naive as well as LPS-injected xCT −/- mice showing a decreased immobility-time in the MTS and in the forced swim test ( c − using SAS ( −/− mice did not display an anti-depressive profile compared to xCT +/+ mice (Mann-Whitney test: immobility time in the MTS: p = 0.1230), and we could not induce this phenotype by chronic inhibition of system x c − using SAS in xCT +/+ mice

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Altered lipid profile, oxidative status and hepatitis B virus interactions in human hepatocellular carcinoma