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Further, the crystal structure of NLRP3 revealed a disulfide bond between conserved cysteine residues in the inflammasome active site, suggesting redox-sensitive activity (Zhou et al., 2011

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Two ER-localized soluble fucosyltransferases—POFUT1 and POFUT2—have been reported to O-fucosylate proteins containing EGF repeats and thrombospondin type I repeats, respectively, in a discriminatory manner where they act only on properly folded substrates