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The rates of amenorrhea observed were in 78.3% and 93.6% women in 2.5 mg and 5 mg mifepristone-treated groups, respectively

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Low ROS levels activate cell survival signaling pathways, such as the unfolded protein response and Nrf2 pathways, whereas high ROS levels activate cell death signaling pathways, such as apoptosis and necroptosis pathways 43