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Second, the strength of tirzepatide’s evidence is exactly what makes an apples-to-apples ranking against an investigational amylin analog impossible: you cannot fairly rank a fully-approved drug against a candidate whose stand-alone efficacy stops at Phase 2

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Some of the findings include the following: In a 2022 trial, subjects taking 1,000mg of urolithin A “exhibited clinically meaningful improvements” in their aerobic endurance and physical performance when compared to subjects who took either 500mg or a placebo.5 A separate 2022 trial examined the effects of 1,000mg urolithin A versus placebo in older adults after four months of daily supplementation

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