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Triptolide suppresses NF-κB-Mediated inflammatory responses and activates expression of Nrf2-Mediated antioxidant genes to alleviate caerulein-induced acute pancreatitis

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Translation of these findings into new treatment concepts using ferroptosis induction in MYCN -amplified neuroblastomas, which is often a deadly disease as a result of multiple drug resistance mechanisms, is still missing due to a lack of compounds with pharmacological properties suitable for in vivo use in humans