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Injected solution of Fraction A from 3 rd chromatography step and purified on 4 th chromatograpy step, detection: UV λ = 280 nm

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‘Hijacking’ of ACE2 by the viral spike and its internalization, may lead to a shift from the protective to the deleterious axis of the RAAS, contributing to the vascular complications observed during COVID-19, such as endothelial cell inflammation 9,10,11